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Index > Protein center > KRT6A(Gene name) > Human
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  • KRT6A (Gene name),
  • Keratin, type II cytoskeletal 6A (Protein name ),  K2C6A_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    KRT6A(K6A;KRT6D);
    Protein name:
    Keratin, type II cytoskeletal 6A;
    Alternative:
    Cytokeratin-6D(CK-6D);Cytokeratin-6A(CK-6A);Type-II keratin Kb6;Keratin-6A(K6A);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Heterodimer of a type I and a type II keratin. KRT6 isomers associate with KRT16 and/or KRT17. Interacts with TCHP.
    Function:
    N/A
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    564
    Sequence:
    50:
    MASTSTTIRS | HSSSRRGFSA | NSARLPGVSR | SGFSSVSVSR | SRGSGGLGGA | 
    100:
    CGGAGFGSRS | LYGLGGSKRI | SIGGGSCAIS | GGYGSRAGGS | YGFGGAGSGF | 
    150:
    GFGGGAGIGF | GLGGGAGLAG | GFGGPGFPVC | PPGGIQEVTV | NQSLLTPLNL | 
    200:
    QIDPTIQRVR | AEEREQIKTL | NNKFASFIDK | VRFLEQQNKV | LETKWTLLQE | 
    250:
    QGTKTVRQNL | EPLFEQYINN | LRRQLDSIVG | ERGRLDSELR | GMQDLVEDFK | 
    300:
    NKYEDEINKR | TAAENEFVTL | KKDVDAAYMN | KVELQAKADT | LTDEINFLRA | 
    350:
    LYDAELSQMQ | THISDTSVVL | SMDNNRNLDL | DSIIAEVKAQ | YEEIAQRSRA | 
    400:
    EAESWYQTKY | EELQVTAGRH | GDDLRNTKQE | IAEINRMIQR | LRSEIDHVKK | 
    450:
    QCANLQAAIA | DAEQRGEMAL | KDAKNKLEGL | EDALQKAKQD | LARLLKEYQE | 
    500:
    LMNVKLALDV | EIATYRKLLE | GEECRLNGEG | VGQVNISVVQ | STVSSGYGGA | 
    550:
    SGVGSGLGLG | GGSSYSYGSG | LGVGGGFSSS | SGRAIGGGLS | SVGGGSSTIK | 
    564:
    YTTTSSSSRK | SYKH
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    Pfam:
    UniGene:
    String:
    KEGG:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Keratin, type II cytoskeletal 6A
    Cat.:
    E10099h
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Keratin, type II cytoskeletal 6A
    Cat.:
    E10099m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Keratin, type II cytoskeletal 6A
    Cat.:
    E10099r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Keratin, type II cytoskeletal 6A
    Cat.:
    U10099h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Keratin, type II cytoskeletal 6A
    Cat.:
    U10099r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Keratin, type II cytoskeletal 6A
    Cat.:
    U10099m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Keratin, type II cytoskeletal 6A
    Polyclonal Antibody for Human Keratin, type II cytoskeletal 6A
    Polyclonal Antibody for Human Keratin, type II cytoskeletal 6A
    Cat.:
    P10099Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Keratin, type II cytoskeletal 6A
    Monoclonal Antibody for Human Keratin, type II cytoskeletal 6A
    Monoclonal Antibody for Human Keratin, type II cytoskeletal 6A
    Protein for Human Keratin, type II cytoskeletal 6A
    Protein for Human Keratin, type II cytoskeletal 6A
    Protein for Human Keratin, type II cytoskeletal 6A

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning and characterization of multiple human genes and cDNAs encoding highly related type II keratin 6 isoforms."
      Takahashi K. , Paladini R.D. , Coulombe P.A.
      J. Biol. Chem.270:18581-18592(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Skin.
    2. 2.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT SER-21
      tissue: Brain.
      tissue: Ovary.
      tissue: Pancreas.
    4. 4.
      Bienvenut W.V. , Vousden K.H. , Lukashchuk N. , Lilla S. , Lange E. , Sumpton D.P.
      Submitted (2008-03) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-9; 31-40; 43-86; 169-204; 208-232; 241-347; 350-369; 379-386; 425-436; 447-475 AND 534-550;CLEAVAGE OF INITIATOR METHIONINE;ACETYLATION AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Lung carcinoma.
    5. 5.
      "The cDNA sequence of a type II cytoskeletal keratin reveals constant and variable structural domains among keratins."
      Hanukoglu I. , Fuchs E.
      Cell33:915-924(1983) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 208-564
    6. 6.
      "Identification of trichoplein, a novel keratin filament-binding protein."
      Nishizawa M. , Izawa I. , Inoko A. , Hayashi Y. , Nagata K. , Yokoyama T. , Usukura J. , Inagaki M.
      J. Cell Sci.118:1081-1090(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TCHP
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    8. 8.
      "Mutation of a type II keratin gene (K6a) in pachyonychia congenita."
      Bowden P.E. , Haley J.L. , Kansky A. , Rothnagel J.A. , Jones D.O. , Turner R.J.
      Nat. Genet.10:363-365(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT PC3 ASN-171 DEL
    9. 9.
      "Novel and recurrent mutations in the genes encoding keratins K6a, K16 and K17 in 13 cases of pachyonychia congenita."
      Terrinoni A. , Smith F.J.D. , Didona B. , Canzona F. , Paradisi M. , Huber M. , Hohl D. , David A. , Verloes A. , Leigh I.M. , Munro C.S. , Melino G. , McLean W.H.I.
      J. Invest. Dermatol.117:1391-1396(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS PC3 VAL-174; ARG-469 AND LYS-472
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